04-08-2024, 01:46 PM
(This post was last modified: 04-08-2024, 03:07 PM by ChrisR.
Edit Reason: formatting
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Cost estimation - financial expenditure for DNA research on ancient finds of human remains
Was this discussed before (at anthrogenica)? As can't recall to have seen some real costs from finished projects. I would guess most research is publicly funded and so transparent, but I do not know where detailed expenditure costs for ancient DNA studies could be listed for (Central) Europe.
When asking a LLM-GPT this was the answer:
So could this be accurate and shallow ancient coverage not cost much more then a "normal 30x WGS"?
What might be the desirable coverage for admixture (7x?) and Y-DNA (15x?)
Was this discussed before (at anthrogenica)? As can't recall to have seen some real costs from finished projects. I would guess most research is publicly funded and so transparent, but I do not know where detailed expenditure costs for ancient DNA studies could be listed for (Central) Europe.
When asking a LLM-GPT this was the answer:
Quote:In general, the cost of WGS for ancient DNA can range from several hundred to several thousand dollars per sample, depending on the sequencing technology and depth of coverage used. For example, shallow coverage sequencing (1x-2x) may cost around 300-500 per sample, while deep coverage sequencing (30x-50x) may cost 1,000-3,000 or more per sample.
It is important to note that the cost of WGS for ancient DNA can be higher than for modern DNA, due to the challenges associated with extracting and preparing ancient DNA samples for sequencing. These challenges can include low DNA yield, DNA degradation, and contamination with modern DNA, all of which can impact the cost and feasibility of the project.
Additionally, the cost of data analysis and interpretation can also be a significant factor in the overall cost of ancient DNA research. This can include bioinformatic analysis of the sequencing data, as well as population genetic and statistical analysis to contextualize the results.
So could this be accurate and shallow ancient coverage not cost much more then a "normal 30x WGS"?
What might be the desirable coverage for admixture (7x?) and Y-DNA (15x?)