Hello everybody
I would ask about methode test mtDNA in 23andME
I believe maybe 23andME according in test mtDNA HVR1+HVR2
its true or wrong
thanks
(05-09-2024, 05:25 AM)Capsian20 Wrote: [ -> ]Hello everybody
I would ask about methode test mtDNA in 23andME
I believe maybe 23andME according in test mtDNA HVR1+HVR2
its true or wrong
thanks
no, it's based on full sequence but they only test about 4,500 out 16,569 sites , some results are wrong subclades specially H haplogroup
(05-09-2024, 03:28 PM)miquirumba Wrote: [ -> ] (05-09-2024, 05:25 AM)Capsian20 Wrote: [ -> ]Hello everybody
I would ask about methode test mtDNA in 23andME
I believe maybe 23andME according in test mtDNA HVR1+HVR2
its true or wrong
thanks
no, it's based on full sequence but they only test about 4,500 out 16,569 sites , some results are wrong subclades specially H haplogroup
Thans you , if its H2a very possible its wrong result , I have been uploaded ( file FTDNA Autosomal ) i got H2a i know arent there SNP mtDNA on file FTDNA ( i only give this note because you said Haplogroup H )
(05-09-2024, 05:06 PM)Capsian20 Wrote: [ -> ] (05-09-2024, 03:28 PM)miquirumba Wrote: [ -> ] (05-09-2024, 05:25 AM)Capsian20 Wrote: [ -> ]Hello everybody
I would ask about methode test mtDNA in 23andME
I believe maybe 23andME according in test mtDNA HVR1+HVR2
its true or wrong
thanks
no, it's based on full sequence but they only test about 4,500 out 16,569 sites , some results are wrong subclades specially H haplogroup
Thans you , if its H2a very possible its wrong result , I have been uploaded ( file FTDNA Autosomal ) i got H2a i know arent there SNP mtDNA on file FTDNA ( i only give this note because you said Haplogroup H )
Family Finder has only 179 mt SNPs and you need at least 3,000 most variable mt SNPs like Genera or Living DNA raw data
Roberta Estes advanced that FTDNA wants to include basic maternal haplogroup prediction in FF next year with more SNPs
(05-09-2024, 05:29 PM)miquirumba Wrote: [ -> ] (05-09-2024, 05:06 PM)Capsian20 Wrote: [ -> ] (05-09-2024, 03:28 PM)miquirumba Wrote: [ -> ]no, it's based on full sequence but they only test about 4,500 out 16,569 sites , some results are wrong subclades specially H haplogroup
Thans you , if its H2a very possible its wrong result , I have been uploaded ( file FTDNA Autosomal ) i got H2a i know arent there SNP mtDNA on file FTDNA ( i only give this note because you said Haplogroup H )
Family Finder has only 179 mt SNPs and you need at least 3,000 most variable mt SNPs like Genera or Living DNA raw data
Roberta Estes advanced that FTDNA wants to include basic maternal haplogroup prediction in FF next year with more SNPs
The good but i think we will get only basic mtDNA example mtDNA V , H , T , J1 ects....
I did some tests on James Lick's site:
https://dna.jameslick.com/mthap/
So far this tool is working fine.
Show Content
Spoiler
Found 5078 markers at 3264 positions covering 19.7% of mtDNA.
Markers found (shown as differences to rCRS):
HVR2: 73G 150T 263G 295T 489C
CR: 750G 1438G 2706G 4216C 4769G 5633T 7028T 7419A 7476T 8277I 8860G 10172A 10398G 11251G 12612G 13708A 14766T 15257A 15452A 15662G 15812A
HVR1: 16069T 16126C 16278T (16519C)
IMPORTANT NOTE: The above marker list is almost certainly incomplete due to limitations of genotyping technology and is not comparable to mtDNA sequencing results. It should not be used with services or tools that expect sequencing results, such as mitosearch.
Best mtDNA Haplogroup Matches:
1) J2b1a6
Defining Markers for haplogroup J2b1a6:
HVR2: 73G (150T) 263G 295T 489C
CR: 750G 1438G 2706G 4216C 4769G 5633T 7028T 7476T 8860G 9016G 9494G 10172A 10398G 11251G 11719A 12612G 13708A 14766T 15257A 15326G 15452A 15662G 15812A
HVR1: 16069T 16126C 16193T 16278T
Supported formats: 23andme, FASTA and other .
Easy to use.
(05-31-2024, 01:38 PM)TanTin Wrote: [ -> ]I did some tests on James Lick's site:
https://dna.jameslick.com/mthap/
So far this tool is working fine.
Show Content
Spoiler
Found 5078 markers at 3264 positions covering 19.7% of mtDNA.
Markers found (shown as differences to rCRS):
HVR2: 73G 150T 263G 295T 489C
CR: 750G 1438G 2706G 4216C 4769G 5633T 7028T 7419A 7476T 8277I 8860G 10172A 10398G 11251G 12612G 13708A 14766T 15257A 15452A 15662G 15812A
HVR1: 16069T 16126C 16278T (16519C)
IMPORTANT NOTE: The above marker list is almost certainly incomplete due to limitations of genotyping technology and is not comparable to mtDNA sequencing results. It should not be used with services or tools that expect sequencing results, such as mitosearch.
Best mtDNA Haplogroup Matches:
1) J2b1a6
Defining Markers for haplogroup J2b1a6:
HVR2: 73G (150T) 263G 295T 489C
CR: 750G 1438G 2706G 4216C 4769G 5633T 7028T 7476T 8860G 9016G 9494G 10172A 10398G 11251G 11719A 12612G 13708A 14766T 15257A 15326G 15452A 15662G 15812A
HVR1: 16069T 16126C 16193T 16278T
Supported formats: 23andme, FASTA and other .
Easy to use.
I used now file 23andME i got V < V12
Quote:1) V12
Defining Markers for haplogroup V12:
HVR2: 72C 263G
CR: 750G 1438G 2706G 4580A 4769G 7028T 7270C 8860G 15326G 15904T
HVR1: 16298C
Marker path from rCRS to haplogroup V12 (plus extra markers):
H2a2a1(rCRS) ⇨ 263G ⇨ H2a2a ⇨ 8860G 15326G ⇨ H2a2 ⇨ 750G ⇨ H2a ⇨ 4769G ⇨ H2 ⇨ 1438G ⇨ H ⇨ 2706G 7028T ⇨ HV ⇨ 72C 16298C ⇨ HV0 ⇨ 15904T ⇨ HV0a ⇨ 4580A ⇨ V ⇨ 7270C ⇨ V12 ⇨ 93G (309.1C) (315.1C) 513A 14629T
Imperfect Match. Your results contained differences with this haplogroup:
Matches(12): 72C 263G 750G 1438G 2706G 4580A 4769G 7028T 7270C 8860G 15326G 15904T
Mismatches(1): 16298T
Extras(3): 93G (309.1C) (315.1C) 513A 14629T
2) V25
Defining Markers for haplogroup V25:
HVR2: 72C 263G
CR: 750G 1438G 2706G 4580A 4769G 7028T 8860G 14629T 15326G 15904T
HVR1: 16298C
Marker path from rCRS to haplogroup V25 (plus extra markers):
H2a2a1(rCRS) ⇨ 263G ⇨ H2a2a ⇨ 8860G 15326G ⇨ H2a2 ⇨ 750G ⇨ H2a ⇨ 4769G ⇨ H2 ⇨ 1438G ⇨ H ⇨ 2706G 7028T ⇨ HV ⇨ 72C 16298C ⇨ HV0 ⇨ 15904T ⇨ HV0a ⇨ 4580A ⇨ V ⇨ 14629T ⇨ V25 ⇨ 93G (309.1C) (315.1C) 513A 7270C
Imperfect Match. Your results contained differences with this haplogroup:
Matches(12): 72C 263G 750G 1438G 2706G 4580A 4769G 7028T 8860G 14629T 15326G 15904T
Mismatches(1): 16298T
Extras(3): 93G (309.1C) (315.1C) 513A 7270C
(05-31-2024, 02:04 PM)Capsian20 Wrote: [ -> ]I used now file 23andME i got V < V12
Show Content
Spoiler
1) V12
Defining Markers for haplogroup V12:
HVR2: 72C 263G
CR: 750G 1438G 2706G 4580A 4769G 7028T 7270C 8860G 15326G 15904T
HVR1: 16298C
Marker path from rCRS to haplogroup V12 (plus extra markers):
H2a2a1(rCRS) ⇨ 263G ⇨ H2a2a ⇨ 8860G 15326G ⇨ H2a2 ⇨ 750G ⇨ H2a ⇨ 4769G ⇨ H2 ⇨ 1438G ⇨ H ⇨ 2706G 7028T ⇨ HV ⇨ 72C 16298C ⇨ HV0 ⇨ 15904T ⇨ HV0a ⇨ 4580A ⇨ V ⇨ 7270C ⇨ V12 ⇨ 93G (309.1C) (315.1C) 513A 14629T
Imperfect Match. Your results contained differences with this haplogroup:
Matches(12): 72C 263G 750G 1438G 2706G 4580A 4769G 7028T 7270C 8860G 15326G 15904T
Mismatches(1): 16298T
Extras(3): 93G (309.1C) (315.1C) 513A 14629T
2) V25
Defining Markers for haplogroup V25:
HVR2: 72C 263G
CR: 750G 1438G 2706G 4580A 4769G 7028T 8860G 14629T 15326G 15904T
HVR1: 16298C
Marker path from rCRS to haplogroup V25 (plus extra markers):
H2a2a1(rCRS) ⇨ 263G ⇨ H2a2a ⇨ 8860G 15326G ⇨ H2a2 ⇨ 750G ⇨ H2a ⇨ 4769G ⇨ H2 ⇨ 1438G ⇨ H ⇨ 2706G 7028T ⇨ HV ⇨ 72C 16298C ⇨ HV0 ⇨ 15904T ⇨ HV0a ⇨ 4580A ⇨ V ⇨ 14629T ⇨ V25 ⇨ 93G (309.1C) (315.1C) 513A 7270C
Imperfect Match. Your results contained differences with this haplogroup:
Matches(12): 72C 263G 750G 1438G 2706G 4580A 4769G 7028T 8860G 14629T 15326G 15904T
Mismatches(1): 16298T
Extras(3): 93G (309.1C) (315.1C) 513A 7270C
Which site or software did you use to generate your results ?